California Environmental Protection Agency Department of Pesticide Regulation Medical Toxicology Branch Summary of Toxicology Data Dicrotophos

Reverse mutation assay: No data gap, no adverse effect In vitro mammalian cell assay: No data gap, possible adverse effect In vivo cytogenetics assay: No data gap, no adverse effect Neurotoxicity: No data gap, possible adverse effect † † Hen neurotoxicity study did not indicate distal delayed neuropathies, but acetylcholinesterase inhibition was flagged as " possible adverse effect " in several rat studies. Toxicology one-liners are attached. All record numbers for the above study types through 280963 (Document No. 299-0069) were examined. This includes all relevant studies indexed by DPR as of Dec. 2, 2014. In the 1-liners below: ** indicates an acceptable study. Bold face indicates a possible adverse effect. ## indicates a study on file but not yet reviewed.